Effect of gold nanoparticle on the microscopic morphology of white blood cell.
نویسندگان
چکیده
BACKGROUND In medicine, there is limited knowledge on the toxicity of nanoparticles. In medicine, there has been limited knowledge on the effect of nanoparticles on the white blood cell. OBJECTIVE To evaluate the effect of gold nanoparticle on the microscopic morphology of white blood cell. SETTING Chulalongkorn Univesity, Bangkok, Thailand. METHOD This study was performed as an experimental study. Mixture of gold nanoparticle solution and blood sample was prepared and analysed. RESULT This work revealed that after mixing the blood sample with gold nanoparticle solution, accumulation of gold nanoparticle in the white blood cell was observed. CONCLUSION The effect of gold nanoparticle on the white blood cell can be detected and this knowledge can be used in cytotoxic drug treatment.
منابع مشابه
Cytotoxity Assessment of Gold Nanoparticle-Chitosan Hydrogel Nanocomposite as an Efficient Support for Cell Immobilization: toward Sensing Application
Cell-based biosensors have become a research hotspot in biosensors and bioelectronics fields. The main feature of cell-based biosensors is the immobilization of living cell on the surface of transducers. Different types of polymers which are used as scaffolds for cell growth should be biocompatible and have reactive functional groups for further attachment of biomolecules. In this work, the cel...
متن کاملSimulation of Cancer Treatment by Gold Nanoparticle-assisted Hyperthermia Applying the Effect of Blood Vessels
This article has no abstract.
متن کاملEngineering Nano-aggregates: β-Cyclodextrin Facilitates the Thiol-Gold Nanoparticle Self-Assembly
The structure and morphology of nonmaterial formed by colloidal synthesis represent a subject of interest as it is a factor deciding the physicochemical properties and biological applications of nanostructures. Among various nanoparticles, gold can develop fractal assembled patterns. Herein, we report a nano-aggregate of a thiol-on-gold self-assembled structure and the influence of β-cyclodextr...
متن کاملEvaluation of Gold Nanoparticle Size Effect on Dose Enhancement Factor in Megavoltage Beam Radiotherapy Using MAGICA Polymer Gel Dosimeter
Background: Gold nanoparticles (GNPs) are among the most promising radiosensitive materials in radiotherapy. Studying the effective sensitizing factors such as nanoparticle size, concentration, surface features, radiation energy and cell type can help to optimize the effect and possible clinical application of GNPs in radiation therapy. In this study, the radiation sensitive polymer gel was use...
متن کاملChitosan/nanosilver Nanofiber Composites with Enhanced Morphology and Microbiological Properties
In recent years natural polymers have been widely used in biomedical applications. Application of natural and biocompatible polymers in wound dressing, medical sutures and tissue engineering are extensively growing. Additional properties are provided when metal nanoparticles such as silver and gold are incorporated in to the fibers. However, nowadays nanofibers due to their inherent properties ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- Cytopathology : official journal of the British Society for Clinical Cytology
دوره 20 2 شماره
صفحات -
تاریخ انتشار 2009